The Sheffield Trophoblastic Disease Centre


The Centre was established in 1973, as part of a national programme, to screen for gestational trophoblastic tumours (a spectrum of disorders including hydatidiform mole and choriocarcinoma) for the North of England and North Wales.

This website offers information for women diagnosed with trophoblastic disease and for medical professionals caring for women with these rare disorders.

The Sheffield Trophoblastic Disease Centre is based at Weston Park Hospital in Sheffield. The centre is run in collaboration with the University of Sheffield and the Cancer Clinical Trials Centre at Weston Park Hospital. Information about the hospital and how to get here can be found on the Weston Park Hospital website.

team2014

The Sheffield Trophoblastic Disease Centre Team

New guidelines for contraception:
  • Effective from 1st January 2014.
  • Oestrogen and/ or progestogens taken between evacuation of the mole and the return to normality of hCG values appear not to increase the risk of invasive mole or choriocarcinoma developing. Therefore women may use oral contraceptives after molar evacuation, before the hCG returns to normal.

In the UK there are three centres involved in the screening programme for trophoblastic disease, the others are at Charing Cross Hospital in London and at Ninewells Hospital in Dundee. The Sheffield and London Centres also treat persistent tumours. Sheffield provides the service the service for the North of England and North Wales.
Logos of The University of Sheffield and Sheffield Teaching Hospitals NHS Trust